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Asimilobine

CAS No. 6871-21-2

Asimilobine ( —— )

Catalog No. M21801 CAS No. 6871-21-2

Asimilobine is an aporphine isoquinoline alkaloid isolated from plant species of Magnolia obobata Thun.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Asimilobine
  • Note
    Research use only, not for human use.
  • Brief Description
    Asimilobine is an aporphine isoquinoline alkaloid isolated from plant species of Magnolia obobata Thun.
  • Description
    Asimilobine is an aporphine isoquinoline alkaloid isolated from plant species of Magnolia obobata Thun. Asimilobine is a dopamine biosynthesis inhibitor and a serotonergic receptor antagonist. Asimilobine shows an antimalarial and anti-cancer activity.
  • In Vitro
    Asimilobine (0.05-0.2 μM; for 24 h) shows a significant inhibition of intracellular dopamine levels in a concentration-dependent manner with an IC50 value of 0.13 μM. Asimilobine (0.15 μM) inhibits tyrosine hydroxylase (TH) and aromatic L-amino acid decarboxylase (AADC) activities at 24 h. Asimilobine also decreases TH mRNA levels and intracellular cyclic AMP levels.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    ——
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    6871-21-2
  • Formula Weight
    ——
  • Molecular Formula
    ——
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

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